Effects of aqueous and alcoholic povidone‐iodine on spores of Bacillus subtilis

Abstract
Spores of B. subtilis NCTC 10073 were examined for susceptibility to 2 proprietary brands of povidone-iodine: an aqueous solution, Betadine, and an alcoholic solution, Videne. Spores were converted to ion-exchange and coat-defective forms. The resistance of these to povidone-iodine was compared and related to uptake. Effects on spore protoplasts and cortex in relation to hexosamine release were also examined. The degree of spore penetration and site of action of povidone-iodine is discussed.