SUXAMETHONIUM CHLORIDE AND MALIGNANT HYPERPYREXIA
- 1 April 1986
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 58 (4) , 447-450
- https://doi.org/10.1093/bja/58.4.447
Abstract
Pure suxamethonium chloride does not produce in vitro contracture of skeletal muscle from swine which are susceptible to malignant hyperpyrexia (MH), but does induce MH in vivo. It is suggested that suxamethonium chloride induces MH because the fasciculations which it causes lead to an increase in the myoplasmic calcium concentration.This publication has 1 reference indexed in Scilit:
- SITE OF THE MUSCLE CELL ABNORMALITY IN SWINE SUSCEPTIBLE TO MALIGNANT HYPERPYREXUBritish Journal of Anaesthesia, 1980