RESULTS OF SURGICAL AND RADIATION THERAPY IN THE TREATMENT OF LIPOSARCOMA ARISING IN AN EXTREMITY

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Abstract
The results of surgical and radiation therapy are analyzed in a retrospective review of liposarcomas arising in an extremity treated at Memorial Sloan-Kettering Cancer Center between 1949 and 1967. The 5 year and 10 year survival rates were 62 per cent and 51 per cent after curative therapy; 27 per cent of patients developed local recurrences and 40 per cent developed metastases. Adjunctive radiation therapy was employed in 11 patients, 9 of whom survived over 5 years (82 per cent). Radiation therapy produced subjective and objective responses in many cases of local recurrences and metastases, with complete regression of tumor and prolonged survival in some instances. A combined surgical and radiotherapeutic approach to these tumors appears to offer distinct advantages, and may have obviated the need for amputation in some cases.

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