Comparison of three physiologically based pharmacokinetic models of benzene disposition
- 31 August 1991
- journal article
- research article
- Published by Elsevier in Toxicology and Applied Pharmacology
- Vol. 110 (1) , 79-88
- https://doi.org/10.1016/0041-008x(91)90291-l
Abstract
No abstract availableKeywords
This publication has 21 references indexed in Scilit:
- Mechanisms of benzene carcinogenesis: Application of a physiological model of benzene pharmacokinetics and metabolismToxicology Letters, 1991
- Uncertainties in Pharmacokinetic Modeling for Perchloroethylene. I. Comparison of Model Structure, Parameters, and Predictions for Low‐Dose Metabolism Rates for Models Derived by Different AuthorsRisk Analysis, 1990
- Precision and sensitivity of pharmacokinetic models for cancer risk assessment: Tetrachloroethylene in mice, rats, and humansToxicology and Applied Pharmacology, 1990
- Evaluation of uncertainty in input parameters to pharmacokinetic models and the resulting uncertainty in outputToxicology Letters, 1989
- Differences in the pathways for metabolism of benzene in rats and mice simulated by a physiological model.Environmental Health Perspectives, 1989
- Metabolite-based internal doses used in a risk assessment of benzene.Environmental Health Perspectives, 1989
- Pharmacokinetically based risk assessment of workplace exposure to benzeneRegulatory Toxicology and Pharmacology, 1989
- An interaction of benzene metabolites reproduces the myelotoxicity observed with benzene exposureToxicology and Applied Pharmacology, 1987
- Recent Advances in the Metabolism and Toxicity of BenzeneCRC Critical Reviews in Toxicology, 1987
- Physiologically Based Pharmacokinetic Modeling: Principles and ApplicationsJournal of Pharmaceutical Sciences, 1983