Anti-globulin antibodies detecting hidden gamma G antigens: characterization of the "pepsin site" by different immune antisera.

  • 1 September 1970
    • journal article
    • Vol. 19  (3) , 511-7
Abstract
The antigenic region of human γG-globulin revealed by pepsin digestion has been studied by means of four different `pepsin agglutinator' (PA) containing sera. Two of these were `naturally occurring' agglutinators found in human and subhuman (baboon) sera respectively. The other two were heteroimmune antisera produced by the immunization of rabbits with human and baboon F(ab′)2 fragments. All of the PAs were agglutinating but not precipitating.