GENETIC CORRELATION OF A MOUSE LIGHT CHAIN VARIABLE REGION MARKER WITH A THYMOCYTE SURFACE ANTIGEN
Open Access
- 1 November 1974
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 140 (5) , 1432-1437
- https://doi.org/10.1084/jem.140.5.1432
Abstract
The inbred and congenic strain distribution of the IH-peptide marker in the variable region of mouse immunoglobulin light chains has been compared with other known genetic markers. A positive correlation was noted between the IH-peptide marker and expression of the Ly-3.1 thymocyte cell surface antigen. This suggests that the locus responsible for IH-peptide expression is genetically linked to the Ly-2 and Ly-3 loci in linkage group XI on chromsome 6 of the mouse.Keywords
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