Raman spectroscopy and normal vibrations of peptides

Publisher Website
Google Scholar
Abstract
Raman and infrared spectra have been recorded on the peptide Gly‐lPro‐Gly‐Gly in its zwitterionic form and on its protected homolog Z‐Gly‐lPro‐Gly‐Gly‐OMe (Z=N‐benzyloxycarbonyl and OMe = methyl ester). Both peptides adopt a type‐II β‐turn conformation into appropriate solvents, that is in dimethylsulfoxide and chloroform respectively.A normal coordinate treatment has been performed on Gly‐lPro‐Gly‐Gly using a modified Urey‐Bradley force field and the characteristic normal modes of vibrations. Their corresponding frequencies have been extracted from experimental investigations.