A murine model for the study of the impact ofAspergillus fumigatus inoculation on the foeto-placental unit

Abstract
Pregnant female BALB/c mice were inoculated intravenously withAspergillus fumigatus conidia in different concentrations (1×101−1×108) on day 10 of pregnancy. Pregnancy was confirmed by the presence of murine alpha-fetoprotein (m-AFP) in the maternal circulation. Conidia inoculation of 1×103 and greater significantly (p lung > kidney > brain > heart.