Vertebrate GABA receptors
- 1 June 1978
- journal article
- review article
- Published by Springer Nature in Neurochemical Research
- Vol. 3 (3) , 263-280
- https://doi.org/10.1007/bf00965574
Abstract
Physiologic-pharmacologic studies in vivo and with tissue cultures have revealed that synaptic GABA receptors exist in the vertebrate CNS. The GABA antagonist, bicuculline, can be used to detect synaptic GABA receptors in both the presence and absence of Na+, even though GABA binding to cerebral subcellular fractions occurs mainly to transport (uptake) receptors in the presence of Na+.Keywords
This publication has 88 references indexed in Scilit:
- Alterations in 3H-GABA binding in Huntington's choreaLife Sciences, 1977
- Suppression of GABA-induced abstinence behaviour in naive rats by morphine and bicucullineLife Sciences, 1977
- Na+-independent binding of GABA to the triton X-100 treated synaptic membranes from cerebellum of rat brainLife Sciences, 1977
- Effects of γ-aminobutyric acid on 33Pi incorporation into rat brain phospholipidsLife Sciences, 1977
- ISOLATION OF HYDROPHOBIC PROTEINS BINDING AMINO ACIDS: γ‐AMINOBUTYRIC ACID BINDING IN THE RAT CEREBRAL CORTEXJournal of Neurochemistry, 1975
- New concepts on the mechanism of action of benzodiazepinesLife Sciences, 1975
- Spontaneous action potentials in isolated guinea-pig cerebellar slices: effects of amino acids and conditions affecting sodium and water uptakeProceedings of the Royal Society of London. B. Biological Sciences, 1973
- Changes in the Na+ - dependent binding of -aminobutyric acid to rat brain particles caused by maturationLife Sciences, 1972
- Bicuculline and Central GABA ReceptorsNature, 1970
- Binding of γ-aminobutyric acid by brain preparationsBiochemical and Biophysical Research Communications, 1961