Neuroprotective Properties of Statins in Cerebral Ischemia and Stroke
- 1 September 1999
- journal article
- review article
- Published by Wolters Kluwer Health in Stroke
- Vol. 30 (9) , 1969-1973
- https://doi.org/10.1161/01.str.30.9.1969
Abstract
Background—The atheroma-retarding properties of β-hydroxy-β-methylglutaryl coenzyme A reductase (HMG-CoA) inhibitors, or “statins,” in both the coronary and carotid arterial beds are well establish...Keywords
This publication has 28 references indexed in Scilit:
- Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages.Journal of Clinical Investigation, 1997
- Inducible Nitric-oxide Synthase and Nitric Oxide Production in Human Fetal Astrocytes and MicrogliaPublished by Elsevier ,1997
- Reduced susceptibility of low density lipoprotein (LDL) to lipid peroxidation after fluvastatin therapy is associated with the hypocholesterolemic effect of the drug and its binding to the LDLAtherosclerosis, 1997
- The Effect of Pravastatin on Coronary Events after Myocardial Infarction in Patients with Average Cholesterol LevelsNew England Journal of Medicine, 1996
- Enlarged Infarcts in Endothelial Nitric Oxide Synthase Knockout Mice are Attenuated by Nitro-L-ArginineJournal of Cerebral Blood Flow & Metabolism, 1996
- Neuroprotective Effects of Human Recombinant Interleukin-1 Receptor Antagonist in Focal Cerebral Ischaemia in the RatJournal of Cerebral Blood Flow & Metabolism, 1996
- Differential regulation by cytokines of human astrocyte nitric oxide productionGlia, 1995
- Pravastatin, lipids, and atherosclerosis in the carotid arteries (PLAC-II)The American Journal of Cardiology, 1995
- Serum Cholesterol Levels and Six-Year Mortality from Stroke in 350,977 Men Screened for the Multiple Risk Factor Intervention TrialNew England Journal of Medicine, 1989
- Interleukin 1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells.The Journal of Experimental Medicine, 1984