Fate of vasopressin and oxytocin in the pulmonary circulation
- 1 August 1969
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Physiology and Pharmacology
- Vol. 47 (8) , 713-717
- https://doi.org/10.1139/y69-121
Abstract
The pulmonary inactivation of lys-8 vasopressin in anesthetized, normal dogs, cats, rabbits, and rats, and that of Pitressin in rats, was studied by means of the systemic pressure response technique. The pulmonary fate of oxytocin was measured in rats by the same technique and, in addition, by means of an in vivo oxytocic assay. The pulmonary inactivation of these three neurohypophyseal peptides was negligible in all instances. The data reinforce the concept that circulating hormones freely cross the pulmonary vascular bed.Keywords
This publication has 0 references indexed in Scilit: