Slow Migrating Proteinase Inhibitors in Human Serum
- 1 January 1984
- journal article
- research article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 365 (1) , 567-570
- https://doi.org/10.1515/bchm2.1984.365.1.567
Abstract
Using a sensitive semi-quantitative electrophoretic-technique on acid-deproteinized serum, 2 previously unrecognized trypsin inhibitors migrating as .beta.2- and .gamma.-globulins, respectively, were found. The 2 inhibitory bands were also detected in native serum. They were not seen in 3 healthy persons but were found in patients with uremia, cancer, inflammatory diseases and collagenosis. Immunological investigations showed no cross-reaction with antibodies against 7 well-knonw proteinase inhibitors. The 2 trypsin inhibitors also inhibited pancreatic elastase.This publication has 4 references indexed in Scilit:
- Purification and some properties of a plasma protein which reacts with an antiserum against urinary trypsin inhibitor-1Scandinavian Journal of Clinical and Laboratory Investigation, 1983
- Electrophoretic Investigations of Acid-Stable Proteinase-Inhibitory Activity in Human SerumHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1983
- Protein Inhibitors of ProteinasesAnnual Review of Biochemistry, 1980
- The Inter-α-Trypsin Inhibitor as Precursor of the Acid-Stable Proteinase Inhibitors in Human Serum and UrineHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1976