Cyclic AMP-dependent Protein Kinase Signaling Modulates Pregnane x Receptor Activity in a Species-specific Manner

This publication has 37 references indexed in Scilit:

• Cyclin-dependent Kinase 2 Negatively Regulates Human Pregnane X Receptor-mediated CYP3A4 Gene Expression in HepG2 Liver Carcinoma Cells
  Journal of Biological Chemistry, 2008
• A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response
  Journal of Clinical Investigation, 2008
• The Traditional Chinese Herbal Remedy Tian Xian Activates Pregnane X Receptor and Induces CYP3A Gene Expression in Hepatocytes
  Drug Metabolism and Disposition, 2008
• Cell Signaling and Nuclear Receptors: New Opportunities for Molecular Pharmaceuticals in Liver Disease
  Molecular Pharmaceutics, 2007
• Human nuclear pregnane X receptor cross-talk with CREB to repress cAMP activation of the glucose-6-phosphatase gene
  Biochemical Journal, 2007
• Nuclear Pregnane X Receptor Cross-talk with FoxA2 to Mediate Drug-induced Regulation of Lipid Metabolism in Fasting Mouse Liver
  Journal of Biological Chemistry, 2007
• The Pregnane X Receptor Gene-Humanized Mouse: A Model for Investigating Drug-Drug Interactions Mediated by Cytochromes P450 3A
  Drug Metabolism and Disposition, 2007
• The role of intracellular signaling in insulin-mediated regulation of drug metabolizing enzyme gene and protein expression
  Pharmacology & Therapeutics, 2007
• Regulation of Constitutive Androstane Receptor and Its Target Genes by Fasting, cAMP, Hepatocyte Nuclear Factor α, and the Coactivator Peroxisome Proliferator-activated Receptor γ Coactivator-1α
  Journal of Biological Chemistry, 2006
• Mutual repression between steroid and xenobiotic receptor and NF- B signaling pathways links xenobiotic metabolism and inflammation
  Journal of Clinical Investigation, 2006