Synaptic reorganization within the human central nervous system following injury
- 1 October 1989
- journal article
- case report
- Published by Journal of Neurosurgery Publishing Group (JNSPG) in Journal of Neurosurgery
- Vol. 71 (4) , 534-537
- https://doi.org/10.3171/jns.1989.71.4.0534
Abstract
✓ Behavioral recovery following brain injury in humans is well recognized; however, the anatomical basis for such recovery has not been demonstrated. Two cases are presented that show reorganization of synaptic connections (plasticity) in the dentate gyrus of human brain following uncal herniation. The neurohistological appearance of these cases is very similar to a well-described animal model of anatomical, physiological, and behavioral recovery following experimental surgical injury.Keywords
This publication has 13 references indexed in Scilit:
- Plasticity of Hippocampal Circuitry in Alzheimer's DiseaseScience, 1985
- The process of reinnervation in the dentate gyrus of the adult rat: A quantitative electron microscopic analysis of terminal proliferation and reactive synaptogenesisJournal of Comparative Neurology, 1983
- Decline in reactive fiber growth in the dentate gyrus of aged rats compared to young adult rats following entorhinal cortex removalBrain Research, 1980
- Plasticity of retinofugal projections after partial lesions of the retina in newborn syrian hamstersJournal of Comparative Neurology, 1979
- Histochemical evidence for a post‐lesion reorganization of cholinergic afferents in the hippocampal formation of the mature catJournal of Comparative Neurology, 1978
- Topographic organization of the projections from the entorhinal area to the hippocampal formation of the ratJournal of Comparative Neurology, 1976
- Axonal regeneration and functional plasticity in the central nervous systemExperimental Neurology, 1974
- Induced acetylcholinesterase-rich layer in rat dentate gyrus following entorhinal lesionsBrain Research, 1972
- Origin and termination of the hippocampal perforant path in the rat studied by silver impregnationJournal of Comparative Neurology, 1972
- Two methods for selective silver impregnation of degenerating axons and their synaptic endings in the central nervous systemBrain Research, 1967