Sex Difference in Pituitary Lactic Dehydrogenase Concentration in Rats1

Publisher Website
Google Scholar
Abstract
The pituitary lactic dehydrogenase (LDH) concentration is higher in the sexually mature female rat than in the male. This difference develops at about the 60th day of life, coincidental with the opening of the vagina. After ovariectomy the pituitary LDH concentration shows a further increase for 1 to 4 days and then declines to levels found in male pituitary. Pituitary LDH has 5 isoenzymes which on electrophoresis do not appear to be different in mobility or in relative amounts in males and females. The larger quantity of enzyme in the pituitary of the female rat can be visualized histochemically; no definite difference in the intracellular localization of the enzyme could be demonstrated. A sex-dependent difference in LDH concentration was not found in adrenal, kidney, lung and liver of rats.

This publication has 0 references indexed in Scilit: