Calcium influx and spontaneous phasic contractions of portal veins after treatment with reserpine, 6-hydroxydopamine, and cocaine
- 1 April 1978
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Physiology and Pharmacology
- Vol. 56 (2) , 199-201
- https://doi.org/10.1139/y78-028
Abstract
Reserpine treatment increased the amplitude of the spontaneous phasic contraction (SPC) of portal veins obtained from rabbit and guinea pig but did not alter that of rat. The amplitude of the SPC of portal veins from these animals was increased after 6-hydroxydopamine (6-OHDA) but was not changed after cocaine treatment. Reserpine-and 6-OHDA-induced changes in portal vein SPC amplitude were accompanied by an increase in 45Ca influx.These results indicate that the elevation in SPC amplitude is accompanied by an increase in calcium influx.This publication has 4 references indexed in Scilit:
- Calcium exchange in vascular smooth muscle, action of noradrenaline and lanthanum.The Journal of Physiology, 1976
- Adverse effects of tris hydrochloride, a commonly used buffer in physiological media.The Journal of Physiology, 1976
- Calcium influx and postjunctional supersensitivity in guinea pig aortic stripsEuropean Journal of Pharmacology, 1976
- Influence of the lonic Environment on Spontaneous Electrical and Mechanical Activity of the Rat Portal VeinCirculation Research, 1967