Abstract
Turneforcidine has been prepared by the oxidation of methyl 7α-hydroxy- 8α-pyrrolizidine-1α-carboxylate to the 7-keto compound and stepwise reduction with hydrogen/platinum and lithium aluminium hydride. 7β- Hydroxy-8α-pyrrolizidine-1β-carboxylic acid is not epimerized by alkali but converted into the stable γ-lactone (VI).

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