Calcium Metabolism in Aging Inhabitants of Mountain versus Seacoast Communities in the Kii Peninsula

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Abstract
A survey was conducted on age-related changes in various measures of Ca metabolism in 609 men and women over the age of 30 (more than 1/2 were over the age of 60) in 2 communities of the Kii Peninsula at the central southern tip of the Japanese mainland. One community was on Oshima Island, with adequate nutritional intake; the other community was in the mountainous Shichikawa district, with a low intake of Ca and protein. The subjects of the Shichikawa study showed shorter stature, higher prevalence of lumbago, thinner clavicular cortex, lower serum levels of P, total protein and cholesterol and a higher level of alkaline phosphatase than did the subjects of the Oshima study. There was no difference in the serum Ca levels.

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