• 1 January 1977
    • journal article
    • research article
    • Vol. 49  (4) , 449-453
Abstract
Estrone, estradiol (E2), progesterone, prostaglandin E (PGE) and prostaglandin F (PGF) were measured simultaneously in uterine and peripheral venous plasma [human] PGE and PGF were determined in endometrial curettage samples. PG levels decreased in the absence of an intact blood supply; therefore, tissue samples were all taken before hysterectomy. The levels of ovarian steroids were higher in uterine venous, compared with peripheral venous plasma. PGF levels were significantly higher (P < 0.01) in secretory endometrium compared with proliferative endometrium and throughout the cycle PGF levels in the endometrium were linearly related to the log10 concentration of E2 in uterine venous blood (P < 0.001). PGE levels remained constant throughout the menstrual cycle.

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