Chiral Dimeric Capsules from N,C-Linked Peptidocalix[4]arenes Self-Assembled through an Antiparallel β-Sheetlike Motif

Abstract
The first example of a calix[4]arene amino acid is reported. It allowed the synthesis of the novel N,C-linked peptidocalix[4]arenes which self-assemble in low-polarity media to give chiral dimeric capsules held together by an antiparallel β-sheetlike hydrogen-bonding motif.