A General Strategy for the Synthesis of Monohydroxy-eicosatetraenoic Acids: Total Synthesis of 5(S)-Hydroxy-6(E),8,11,14(Z)-eicosatetraenoic Acid (5-HETE) and 12(S)-Hydroxy-5,8,14(Z), 10(E)-eicosatetraenoic Acid (12-HETE)
- 1 January 1986
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1986 (04) , 344-347
- https://doi.org/10.1055/s-1986-31612
Abstract
Stereocontrolled total syntheses of 5(S)-hydroxy-6(E),8, 11,14(Z)-eicosatetraenoic acid (5-HETE) and 12(S)hydroxy-5,8,14 (Z), 10(E)-eicosatetraenoic acid (12-HETE) via palladium(0)-copper(I) coupling technology are described.Keywords
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