Molecular and biological constraints on ligand-binding affinity and specificity
- 1 January 1997
- journal article
- review article
- Published by Wiley in Biopolymers
- Vol. 44 (2) , 181-198
- https://doi.org/10.1002/(sici)1097-0282(1997)44:2<181::aid-bip5>3.0.co;2-r
Abstract
Interactions between biological macromolecules have characteristic values of affinity and specificity that are set according to the biological function that is served by the interaction in the organism. Here we examine the molecular mechanisms that are used to achieve the required values of affinity and specificity in various biological systems.Keywords
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