Sex Hormone Control Mechanisms. II. Influence of Estrogen and Progesterone on the Activities of Key Enzymes Involved in the Carbohydrate Metabolism of Chicken (Gallus domesticus) Oviducts

Publisher Website
Google Scholar
Abstract
Sex hormones were administered to chicks by repeated intramuscular injections, and the activities of certain enzymes of the oviduct were determined and compared with those of nontreated chicks and those of mature laying and nonlaying hens. The administration of estrogen in combination with progesterone resulted in enhanced activities of phosphofructokinase (ATP : D-fructose-6-phosphate 1-phosphotransferase, EC 2.7.1.11), aldolase (fructose-1,6-diphosphatase D-glyceraldehyde-3-phosphate-lyase, EC 4.1.2.13), and fructose-1,6-diphosphatase (D-fructose-1,6-diphospnate 1-phosphohydrolase, EC 3.1.3.11). Furthermore, estrogen treatment alone resulted in a lesser, but significant, response in phosphofructokinase and aldolase activities and no response in fructose-1,6-diphosphatase activity, while progesterone administered alone had no effect. The data indicate that in addition to enhancing the protein synthetic capacity of chick oviduct cells, estrogen or a combination of estrogen and progesterone also regulate, either directly or indirectly, the metabolic activity of these oviduct cells by increasing the activity of some enzymes involved in carbohydrate metabolism.

This publication has 0 references indexed in Scilit: