Modifying Human Thymidylate Kinase to Potentiate Azidothymidine Activation
Open Access
- 1 December 1999
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 274 (50) , 35289-35292
- https://doi.org/10.1074/jbc.274.50.35289
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- Crystal Structure of Yeast Thymidylate Kinase Complexed with the Bisubstrate Inhibitor P1-(5‘-Adenosyl) P5-(5‘-Thymidyl) Pentaphosphate (TP5A) at 2.0 Å Resolution: Implications for Catalysis and AZT Activation,Biochemistry, 1998
- Improving AZT efficacyNature Medicine, 1998
- Use of Herpes Simplex Virus Thymidine Kinase to Improve the Antiviral Activity of ZidovudineVirology, 1997
- The bottleneck in AZT activationNature Medicine, 1997
- Essential Lysine Residues in the N-Terminal and the C-Terminal Domain of Human Adenylate Kinase Interact with Adenine Nucleotides As Found by Site-Directed Random Mutagenesis†,¶,#Biochemistry, 1997
- Human dTMP Kinase: Gene Expression and Enzymatic Activity Coinciding with Cell Cycle Progression and Cell GrowthDNA and Cell Biology, 1994
- The P-loop — a common motif in ATP- and GTP-binding proteinsTrends in Biochemical Sciences, 1990
- Calcium binding sites in tomato bushy stunt virus visualized by laue crystallographyJournal of Molecular Biology, 1990
- Induced-fit movements in adenylate kinasesJournal of Molecular Biology, 1990
- [64] Guanylate kinases from human erythrocytes, hog brain, and rat liverPublished by Elsevier ,1978