Prognostic value of Langerhans cells in the epidermis of HIV patients
- 1 April 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 118 (4) , 481-486
- https://doi.org/10.1111/j.1365-2133.1988.tb02456.x
Abstract
We measured the number of Langerhans cells in clinically normal epidermis and the number of T4 lymphocytes in the plasma in 24 patients infected with HIV, and related these to the stage of the disease. A correlation is demonstrated between the numbers of Langerhans cells and T4 lymphocytes. Numbers of Langerhans cells were lower in patients with disease stages III and IV than in those with disease stage II. Thus Langerhans cell numbers could be of prognostic value in this disease.This publication has 11 references indexed in Scilit:
- HIV TRANSMISSION AND SKIN GRAFTSThe Lancet, 1987
- Epidermal Langerhans Cells-A Target for HTLV-III/LAV InfectionJournal of Investigative Dermatology, 1987
- In vitro infection of human monocytes with human T lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV).The Journal of Immunology, 1986
- EXPRESSION OF HLA-DR AND T6 ANTIGENS ON KERATINOCYTES AND DENDRITIC CELLS - A COMPARATIVE IMMUNOHISTOCHEMICAL STUDY1986
- Leu-3/T4 Expression on Epidermal Langerhans Cells in Normal and Diseased SkinJournal of Investigative Dermatology, 1986
- Intercellular distribution of HLA-DR and T6 antigens in the epidermis of various dcrmatosesBritish Journal of Dermatology, 1985
- FOLLICULAR DENDRITIC CELLS AND VIRUS-LIKE PARTICLES IN AIDS-RELATED LYMPHADENOPATHYThe Lancet, 1984
- Selective Tropism of Lymphadenopathy Associated Virus (LAV) for Helper-Inducer T LymphocytesScience, 1984
- Reduced Langerhans’ Cell Ia Antigen and ATPase Activity in Patients with the Acquired Immunodeficiency SyndromeNew England Journal of Medicine, 1984