Chromosomes and causation of human cancer and leukemia. XIV. Origin of a large number of markers in a cancer
Open Access
- 1 February 1976
- Vol. 37 (2) , 776-782
- https://doi.org/10.1002/1097-0142(197602)37:2<776::aid-cncr2820370225>3.0.co;2-g
Abstract
A cancerous effusion from a patient with cancer of the breast, with a high modal number of chromosomes (81–83) and with 11–13 abnormal chromosomes (markers) of eight different origins, has been examined in detal karyotypically with C‐, G‐, and Q‐banding techniques. Except for a rare chromosome, all the normal chromosomes were identified and, more importantly, the origin of all markers was ascertained. This study indicates the feasibility of identifying all the chromosomes in cancer cells, even in those with highly polyploid and complicated chromosome constitutions.This publication has 12 references indexed in Scilit:
- NON-RANDOM REPRESENTATION OF CHROMOSOME TYPES IN HUMAN TUMOR STEMLINESHereditas, 2009
- Karyotype patterns in human meningiomasHereditas, 2009
- A simple technique for demonstrating centromeric heterochromatinExperimental Cell Research, 1972
- Marker Band in One Chromosome 14 from Burkitt LymphomasNature, 1972
- The use of proteolytic enzymes for the mapping of structural rearrangements in the chromosomes of manChromosoma, 1972
- A RAPID BANDING TECHNIQUE FOR HUMAN CHROMOSOMESThe Lancet, 1971
- Differential binding of alkylating fluorochromes in human chromosomesExperimental Cell Research, 1970
- The Prognostic Significance of Chromosome Abnormalities in Colon TumorsAnnals of Internal Medicine, 1967
- A SIMILAR MARKER CHROMOSOME IN TESTICULAR TUMOURSThe Lancet, 1966
- Chromosomes and CancerNature, 1966