Fibrin glue application in conjunction with tetracycline root conditioning and coronally positioned flap procedure in the treatment of human gingival recession defects
- 1 September 1996
- journal article
- clinical trial
- Published by Wiley in Journal of Clinical Periodontology
- Vol. 23 (9) , 861-867
- https://doi.org/10.1111/j.1600-051x.1996.tb00624.x
Abstract
A split-mouth clinical study was designed to determine the effect of fibrin glue (FG) in addition to tetracycline HCI (TTC) root conditioning and the coronally positioned flap (CPF) procedure in the treatment of maxillary buccal recession defects. 11 patients presenting with a pair of Class I or II recession defects were selected. After initial therapy, defect-specific and full-mouth oral hygiene standards and gingival condition, recession depth, recession width, probing depth, attachment level, and width of keratinized gingiva were recorded. The surgical procedure included elevation of a full split thickness flap, root debridement and root conditioning with a 10 mg/ml TTC solution for 4 minutes. According to a randomization list, in each patient, 1 defect was treated with topical FG application, while the paired defect did not receive FG. The flap was adapted and sutured coronally to the cemento-enamel junction without tension. Healing was evaluated 6 months postsurgery. Significant recession depth reduction and attachment gain were observed for both treatments. Average root coverage amounted to 65% in FG treated defects and 55% in defects treated with TTC conditioning only. There were no clinical and statistical significant differences between the treatments for any parameter considered. This study suggests that FG may not meaningfully enhance the outcome of the CPF procedure with TTC root conditioning.Keywords
This publication has 50 references indexed in Scilit:
- Blood Coagulation Factors in Periodontal Pathophysiology: A Review with Emphasis on the Role of ThrombinSeminars in Thrombosis and Hemostasis, 1992
- Repair of periodontal furcation defects in beagle dogs following reconstructive surgery including root surface demineralization with tetracycline hydrochloride and topical fibronectin applicationJournal of Clinical Periodontology, 1988
- Regeneration of the connective tissue attachment on surgically exposed roots using a fibrin-fibronectin adhesive system. An experimental study on the baboon (Papio ursinus)Journal of Periodontal Research, 1987
- Healing after Application of Tissue‐Adhesive Material to Denuded and Citric Acid‐Treated Root SurfacesThe Journal of Periodontology, 1986
- Treatment of Localized Gingival Recessions: Part III. Comparison of Results Obtained With Lateral Sliding and Coronally Repositioned FlapsThe Journal of Periodontology, 1978
- Treatment of Localized Gingival Recessions: Part II. Coronally Repositioned Flap with a Free Gingival GraftThe Journal of Periodontology, 1978
- Blood Supply of Human Gingiva Following Periodontal Surgery: A Fluorescein Angiographic StudyThe Journal of Periodontology, 1977
- Thrombin potentiates the mitogenic response of cultured fibroblasts to serum and other growth promoting agentsJournal of Cellular Physiology, 1977
- Coronal Positioning of a Previously Placed Autogenous Gingival GraftThe Journal of Periodontology, 1977
- Periodontal Disease in Pregnancy II. Correlation Between Oral Hygiene and Periodontal ConditionActa Odontologica Scandinavica, 1964