Iridium(III)-Induced Isomerization of 2-Substituted Pyridines to N-Heterocyclic Carbenes

Abstract
Steric strains (F-strain or front-strain) in the acid-base interaction between the Lewis acid [TpMe2Ir(C6H5)2] and 2-substituted pyridines Lewis bases, are responsible for the stabilization of the C-adducts (2) of the respective pyridine carbene tautomers over the expected N-adducts.

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