Vitiligo treated with topical clobetasol propionate

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Abstract
Patients (75) with vitiligo were treated with intermittent topical applications of clobetasol propionate for varying times within a 3-yr period. The best results occurred in the facial lesions of Asian or black patients. Repigmentation of 90-100% was achieved in > 80% of patients with vitiligo of the face and > 40% of patients with vitiligo on other parts of the body. Progressive repigmentation continued even after the treatment stopped. Intermittent therapy helped to avoid the problems of adverse local effects from the use of potent adrenal steroids.

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