Basic Concepts of the Mechanism of Action of Peptide Hormones

Abstract
The diverse effects of peptide and protein hormones upon their target cells are now recognized to be mediated by a series of biochemical events which link the primary site of peptide hormone action, the plasma membrane, with a variety of target cell responses. Topics covered in this review are peptide hormone receptors, hormonal activation of adenylate cyclase, cyclic AMP and peptide hormone action and the role of protein kinase in peptide hormone action.