Combined Adrenergic Receptor Blockade and Circulating Catecholamines in Hemorrhagic Shock
- 1 January 1971
- journal article
- Published by S. Karger AG in European Surgical Research
- Vol. 3 (6) , 378-388
- https://doi.org/10.1159/000127584
Abstract
In dogs, premedication with phenoxy-benzamine and dl-propranolol effectively revived an otherwise fatal period of hypertension. The effect of this combined medication was not related to the α-adrenergic receptor blocking activity of phenoxybenzamine but to some of its unidentified actions. The β-blocking activity of dl-propranolol appeared to be essential in producing the effect.Keywords
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