Abstract
Over the past year, chemists in the United States and Ireland have taken initial steps at creating designer materials in which DNA and other organic molecules help connect tiny inorganic particles to create exquisitely organized structures with surprising new properties. Now, in this issue of Science, researchers at Northwestern University in Evanston, Illinois, present the first large-scale device embodying this strategy: a sensor, made from a web of DNA and gold particles, that changes color when it detects a precise strand of DNA.

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