Prognosis of patients with cirrhosis and chronic liver disease admitted to the medical intensive care unit
- 1 July 1988
- journal article
- research article
- Published by Wolters Kluwer Health in Critical Care Medicine
- Vol. 16 (7) , 671-678
- https://doi.org/10.1097/00003246-198807000-00005
Abstract
Patients with hepatic failure admitted to the medical ICU (MICU) generally have a poor prognosis. To determine if there were readily identifiable clinical factors associated with a high predictive value for outcome, we reviewed retrospectively the charts of 100 patients with serious liver disease admitted to the MICU. The overall mortality of the group was 64%. We found that Child's class, a need for mechanical ventilation, and an elevated serum creatinine had the greatest prognostic significance. Ninety-one percent of the patients receiving assisted ventilation, 89% of the patients in Child's class C, and 93% of the patients with creatinine values > 1.3 mg/dl died during their MICU admission. Furthermore, a multivariant regression analysis indicated that patients in Child's class C receiving mechanical ventilation who had an abnormal serum creatinine (>1.3 mg/dl) during the first 72 h in the MICU had only a 2% survival rate.Keywords
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