A protein of squamous keratinising epithelium from odontogenic keratocyst fluid

Abstract
Fluid from odontogenic keratocysts was analysed. The major protein fraction with a mobility anodal to albumin on electrophoresis was shown not to be albumin or pre-albumin but a non-serum protein. Using an antiserum to keratocyst fluid absorbed with human serum, non-serum components of the odontogenic keratocyst fluid were localised in squamous keratinising epithelia, principally in the upper layers. The same antiserum showed immunolocalisation in squamous cell carcinoma of skin and cervix. No localisation was seen in normal non-squamous epithelia, in liver, stomach and colon or in non-keratinising squamous epithelial cysts of the jaw.