Protection Against Guinea Pig Hepatomas by Pretreatment With Subcelluar Fractions of Mycobacterium bovis (BCG)2
- 1 May 1974
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 52 (5) , 1643-1645
- https://doi.org/10.1093/jnci/52.5.1643
Abstract
A methanol-extraction residue and a supernatant of sonically disrupted cells were derived from killed BCG. Pretreatment with these substances prevented progressive development of line-10 hepatocarcinoma in a significant proportion of syngeneic strain-2 Sewall-Wright guinea pigs challenged with sufficient neoplastic cells to cause fatal disease in all the controls.Keywords
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