Biological effects of a purified lipopolysaccharide from Bacteroides gingivalis
- 1 February 1983
- journal article
- research article
- Published by Wiley in Journal of Periodontal Research
- Vol. 18 (1) , 40-49
- https://doi.org/10.1111/j.1600-0765.1983.tb00333.x
Abstract
Lipopolysaccharide (LPS) has been purified from Bacteroides gingivalis. The purity of this LPS is evidenced on ultracentrifugation, immunoelectrophoresis, and chemical analyses. On comparison with LPS from aerobic enteric organisms, LPS from Bacteroides gingivalis exhibits minimal potency when tested for pyrogenicity in rabbits and mitogenicity in mouse spleen cells. On the other hand, purified LPS from Bacteroides gingivalis exhibits high potency in its ability to stimulate 45Ca release from prelabeled fetal rat bones and to inhibit Ca influx into osteoclast‐like cells.This publication has 31 references indexed in Scilit:
- Characterization of Bacteroides gingivalis by direct fluorescent antibody staining and cellular fatty acid profilesCanadian Journal of Microbiology, 1982
- Differences in lymphoproliferative responses to the bacterium Actinomyces viscosus in various mammalian speciesArchives of Oral Biology, 1982
- The predominant cultivable subgingival flora of beagle dogs following ligature placement and metronidazole therapyJournal of Periodontal Research, 1981
- Interactions between bacterial endotoxin and other stimulators of bone resorption in organ cultureJournal of Periodontal Research, 1981
- Subgingival microflora and periodontal diseaseJournal of Clinical Periodontology, 1979
- A new and improved microassay to determine 2-keto-3-deoxyoctonate in lipopolysaccharide of gram-negative bacteriaAnalytical Biochemistry, 1978
- Isolation of a lipid a bound polypeptide responsible for LPS- initiated mitogenesis of C3H/HeJ spleen cellsThe Journal of Experimental Medicine, 1976
- The lipoprotein of the outer membrane of Escherichia coli: a B-lymphocyte mitogen.The Journal of Experimental Medicine, 1975
- Procedure for determining heptose and hexose in lipopolysaccharidesAnalytical Biochemistry, 1972
- Endotoxin: Stimulation of Bone Resorption in Tissue CultureScience, 1970