HAS THE NEW ANTIDIABETIC DRUG, N1-SULPHANILYL-N2-N-BUTYLCARBAMIDE GOITROGENIC PROPERTIES?
- 1 December 1956
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 23 (4) , 433-436
- https://doi.org/10.1530/acta.0.0230433
Abstract
The new anti-diabetic drug, N1-sulphanilyl-N2-n-butylcarbamide, was somewhat goitrogenic in the rat at a daily oral dose of 0.5 g/kg of body weight. The thyroids not only increased in weight but appeared to be histologically more active. The serum protein-bound iodine was lower in the experimental animals than in the controls.Keywords
This publication has 2 references indexed in Scilit:
- CLINICAL DETERMINATION OF PROTEINBOUND IODINE IN PLASMA*†Journal of Clinical Endocrinology & Metabolism, 1950
- The Effect of Sulfanilylguanidine on the Thyroid of the RatScience, 1941