H2Breath Test for Lactase Deficiency

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To the Editor: We read with considerable interest the study by Newcomer and his colleagues,1 in which breath hydrogen rise after lactose ingestion was found to be the most accurate indirect determinant of lactase deficiency. Using an end-expiratory technic, we have also found excellent agreement between breath hydrogen and established tests for hypolactasia2 and have subsequently used the technic for diagnosis of hyposucrasia with similar accuracy.3 However, we should like to make three points.The hydrogen collecting technic used in this study is a highly accurate method but has the disadvantage of size, complexity and rebreathing time, making it . . .

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