The use of nicotine gum during cessation of smoking

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Abstract
The authors present three case studies which suggest that smoking withdrawal symptoms in certain individuals may be due to removal of nicotine per se, implying that smokers may develop a true physical dependence on cigarettes. Nicotine replacement by use of an experimental chewing gum containing nicotine in various dosages successfully prevented or alleviated the abstinence symptoms of the subjects studied.

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