The lipoids of spleen and liver in various types of lipoidosis

Abstract
The lipids of liver and spleen in 3 cases of Gaucher''s disease were analyzed and compared with the findings in 2 cases of Niemann-Pick''s disease and with normals. The classification of these diseases according to the chemical nature of the lipids deposited, is criticized. The various shifts in lipid distribution are explained by deficiency of lipolytic enzymes. Deficiency of liver esterase is demonstrated experimentally in these and similar cases.

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