Silencing of antiapoptotic survivin gene by multiple approaches of RNA interference technology
Open Access
- 1 March 2004
- journal article
- research article
- Published by Taylor & Francis in BioTechniques
- Vol. 36 (3) , 450-460
- https://doi.org/10.2144/04363rr01
Abstract
Silencing of mammalian gene expression by RNA interference (RNAi) technology can be achieved using small interfering RNA (siRNA) or short hairpin RNA (shRNA). However, the relative effectiveness of... Interferin’ with Survivin RNA interference (RNAi) is a biological phenomenon that entails the degradation of mRNA by homologous double-stranded RNA; the underlying mechanism of RNAi has been harnes...Keywords
This publication has 23 references indexed in Scilit:
- Gene silencing in mammals by small interfering RNAsNature Reviews Genetics, 2002
- RNA interferenceNature, 2002
- Gene silencing by double-stranded RNACurrent Opinion in Cell Biology, 2001
- Post-transcriptional gene silencing by double-stranded RNANature Reviews Genetics, 2001
- RNA interference is mediated by 21- and 22-nucleotide RNAsGenes & Development, 2001
- Sensitive assay of RNA interference in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as targetFEBS Letters, 2000
- dsRNA-mediated gene silencing in cultured Drosophila cells: a tissue culture model for the analysis of RNA interferenceGene, 2000
- RNAiCell, 2000
- HOW CELLS RESPOND TO INTERFERONSAnnual Review of Biochemistry, 1998
- Role of the double-stranded RNA-activated protein kinase (PKR) in cell regulationBiochemical Society Transactions, 1997