Pediatric Renal Cell Carcinomas: Where Do They Fit in the New Histologic Classification of Renal Cell Carcinoma?
- 1 May 2000
- journal article
- case report
- Published by Wolters Kluwer Health in Advances in Anatomic Pathology
- Vol. 7 (3) , 135-140
- https://doi.org/10.1097/00125480-200007030-00001
Abstract
Genetic, immunohistochemical, and histologic data has led to the reclassification of renal cell carcinoma in the last decade. Recent studies suggest that renal cell carcinomas in children and young adults may represent a distinct group of tumors. These tumors have unique genetic findings (most commonly t(x;1)(p11:q21)), a predominantly papillary architecture, numerous calcifications, granular cytoplasm, and a possible relationship with neuroblastoma.Keywords
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