Studies in Calcium Absorption: Initial Entry of Calcium into the Gastrointestinal Tract in Hyperparathyroidism and in a Case of Renal Tubular Acidosis

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Abstract
Gastrointestinal (GI) absorption of radiocalcium was measured by the application of a computerized deconvolution technique to data obtained by external arm counting. When compared to normals, hyperparathyroid subjects displayed an exaggerated rate of initial entry of calcium into the GI tract. Total tracer absorbed was also increased. A similar increase in the rate of initial entry of calcium and total calcium absorbed from the GI tract was found in a non-hyperparathyroid subject with distal tubular acidosis of the adult type. It is concluded that in addition to the abnormal function of renal tubular cells in the handling of hydrogen ion there may be in this case, and possibly in others with renal tubular acidosis, an abnormality in the handling of calcium by the GI cells.

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