SICKLE-CELL-ANEMIA IN TURKEY - EVALUATION OF 97 CASES (WITH PARENTS FINDINGS)

  • 1 January 1977
    • journal article
    • research article
    • Vol. 19  (1) , 85-92
Abstract
The hematological and clinical data in 97 sickle-cell anemia cases and hematological findings of their parents are reported. Despite the low Hb values of the patients, they tolerated their anemia and rarely required blood transfusions. The Hb F levels of the patients were in general higher than African origin SS anemia patients but lower than the Shiite Saudi Arabians. In most of the cases the concentration of Hb F did not seem to influence the Hb concentration of the patients. Serum Fe was unexpectedly decreased in 22% of the patients. Osmotic fragility was decreased in 100% of the patients and in 83.5% of the parents. The prevalence of G-6-PD [glucose-6-phosphate dehydrogenase] deficiency was 21.2% in male patients and 15.6% in the parents.