Reactions of Natives of Okinawa and of American Personnel, to Skin Tests with Test Antigen Prepared from Microfilariae of Dirofilaria Immitis

Abstract
Summary Over 400 patients were tested with an antigen prepared from the microfilariae of D. immitis. The optimal dilution for testing was determined, and the varied responses in different stages of filariasis were demonstrated. Its activity in comparison to that of the adult worm antigen was shown, and its limitation and advantages were discussed. The role of intestinal and somatic helminths in eliciting nonspecific reactions was appraised.