Dietary Bile Acids and Lipid Metabolism. I. Influence on Lipids and Liver Size of Chicks

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Abstract
Summary Dietary lithocholic acid elevated plasma cholesterol and lipid phosphorus levels, and increased liver size of growing chicks. In cholesterol-fed chicks, lithocholic acid depressed liver lipid and cholesterol levels. The effects of lithocholic acid were partially reversed by cholic acid in chicks fed a cholesterol-free diet and almost completely reversed in chicks fed cholesterol. The plasma cholesterol level of cholesterol-fed chicks was increased by cholic acid feeding.