The mechanism of adenosine diphosphate induced platelet aggregation: binding to platelet receptors and inhibition of binding and aggregation by prostaglandin E1

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Abstract
1. Normal human blood platelets in stirred plasma were incubated with [14C]ADP for 10-360 sec and the aggregation responses were correlated with platelet bound radioactivity, the platelets being separated from the plasma within 25 sec of the end of the experiment.