Combined Platelet‐Leukapheresis: A Technique for Preparing Separate Platelet and Granulocyte‐Platelet Units from Single Donors
- 4 March 1979
- journal article
- research article
- Published by Wiley in Transfusion
- Vol. 19 (2) , 206-209
- https://doi.org/10.1046/j.1537-2995.1979.19279160296.x
Abstract
One donor can provide separate platelet and granulocyte-platelet units that have the potential to fulfill the needs of 2 recipients. Combined platelet and leukapheresis were performed in the presence of hydroxyethyl starch and citrate employing the Hemonetics Model 30 Blood Separator. Platelets and granulocytes were separated subsequently by centrifugation and 2 individual units were prepared for transfusion. The platelet units contained a mean of 4.4 .times. 1011 platelets/unit and were nearly devoid of leukocytes. The combined granulocyte-platelet units contained a mean of 7.38 .times. 109 neutrophils/unit and 3.06 .times. 1011 platelets/unit. Thus, 2 separate units containing sufficient numbers of cells for transfusion can be obtained from pheresis of 1 donor.This publication has 7 references indexed in Scilit:
- Effect of Hydroxyethyl Starch on Platelet Function Following Granulocyte Collection Using the Continuous Flow Cell SeparatorTransfusion, 1977
- Discontinuous Flow Centrifugation Leukapheresis and Neutrophil FunctionTransfusion, 1977
- Hydroxyethyl starch and prednisone as adjuncts to granulocyte collectionTransfusion, 1977
- A Standardized Technique for Efficient Platelet and Leukocyte Collection Using the Model 30 Blood ProcessorTransfusion, 1976
- Use of Hydroxyethyl Starch To Improve Granulocyte Collection in the Latham Blood ProcessorTransfusion, 1975
- Correction of poor platelet transfusion responses with leukocyte-poor HL-A-matched platelet concentratesBlood, 1975
- Increased Granulocyte Collection with the Blood Cell Separator and the Addition of Etiocholanolone and Hydroxyethyl StarchTransfusion, 1974