Effect of initial storage at room temperature on human red blood cell ATP, 2,3‐DPG, and viability
- 4 March 1977
- journal article
- research article
- Published by Wiley in Transfusion
- Vol. 17 (2) , 147-150
- https://doi.org/10.1046/j.1537-2995.1977.17277151919.x
Abstract
The concentrations of ATP and 2,3-DPG [diphosphoglycerate] and posttransfusion viability were measured in human red blood cells exposed for 1, 4 and 7 h to room temperature before refrigerated storage for 21 days. No effect of room temperature storage was observed on ATP or viability. Decrease in 2,3-DPG was accelerated by room temperature exposure, but the differences in 2,3-DPG were small and unlikely to have a significant adverse effect on red blood cell O2 delivery. Delays of up to 7 h in refrigeration of blood do not appear to have serious adverse effects on red blood cell viability or function.This publication has 7 references indexed in Scilit:
- A Protocol for Cryoprecipitate ProductionTransfusion, 1975
- Recommended Methods for Radioisotope Red Cell Survival StudiesBlood, 1971
- Studies on Stored Whole BloodTransfusion, 1970
- An Enzymatic Assay of 2,3 - Diphosphoglycerate in BloodScandinavian Journal of Clinical and Laboratory Investigation, 1969
- A Comparison of Normal Red Cell ATP Levels as Measured by the Firefly System and the Hexokinase SystemBlood, 1967
- Effect of organic and inorganic phosphates on the oxygen equilibrium of human erythrocytesArchives of Biochemistry and Biophysics, 1967
- Studies on Erythrocyte Glycolysis I. Determination of the Glycolytic Intermediates in Human Erythrocytes*The Journal of Biochemistry, 1965