Characterizations of Long-term Oxycodone/Acetaminophen Prescriptions in Veteran Patients
Open Access
- 22 November 2004
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 164 (21) , 2361-2366
- https://doi.org/10.1001/archinte.164.21.2361
Abstract
The long-term use of opioids for the treatment of chronic pain of nonmalignant origin has been generally supported by specialists in pain management as a less than ideal but often necessary and humane course of treatment.1-4 The main theses presented are quite consistent, specifically that patients without cancer deserve maximum treatment for chronic pain, that fears of consequential clinical dependencies are generally not warranted, and that management problems and liability risks can be reduced by following established published guidelines (eg, from the American Academy of Pain Medicine and American Pain Society [1996]5 and the Federation of State Medical Boards of the United States Inc [1998]6). Furthermore, high-risk patients for opioid prescriptions may already have overt substance abuse, psychopathologic conditions, multiple and ill-defined complaints, and drug-seeking behaviors that alert physicians either to not prescribe these drugs or to do so within very strict guidelines. However, other authors, typically from an addiction medicine perspective, have cited the medical, psychological, and social difficulties inherent in long-term opioid prescribing.7-10 Furthermore, the risk of drug diversion for “street” use may concern practitioners because nonmedicinal use of opioids has increased substantially among street-drug abusers.11 Hence, long-term prescribing of opioid drugs for the managementof chronic, nonmalignant pain may seem necessary but typically remains worrisome for physicians who either start or are obliged to continue this course of treatment.This publication has 9 references indexed in Scilit:
- Validity of Information on Comorbidity Derived From ICD-9-CCM Administrative DataMedical Care, 2002
- Assessing the Risks and Benefits of Benzodiazepines for Anxiety Disorders in Patients with a History of Substance Abuse or DependenceThe American Journal on Addictions, 2001
- Prescription Opiate Abuse in Chronic Pain Patients: Clinical Criteria, Incidence, and PredictorsThe Clinical Journal of Pain, 1997
- Benzodiazepine Misuse by Drug AddictsAnnals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1997
- Long-term opioid therapy: Assessment of consequences and risksJournal of Pain and Symptom Management, 1996
- Appropriateness of Medication Prescribing in Ambulatory Elderly PatientsJournal of the American Geriatrics Society, 1994
- Chronic use of opioid analgesics in non-malignant pain: Report of 38 casesPain, 1986
- The Chronic Pain Syndrome: Misconceptions and ManagementAnnals of Internal Medicine, 1980
- Drug use and misuse in operant pain patientsAddictive Behaviors, 1979